1.27: Cardiac and Muscle Disease
- Page ID
- 38607
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\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)- CK-MB activity and troponin I levels peak at 18-24 hrs. post-MI and are usually normal by 24-36 hrs.
- True
- False
- LD “flip” (LD1 > LD2) or LD total activity is a recommended marker for myocardial infarction.
- True
- False
- The best system for the collection of blood samples to rule out AMI is:
- 0,2,4,6,8 and 24 hrs. post-admission
- 0,6,12 and 12 hrs. post-admission
- 0,24,48 and 72 hrs. post-admission
- 0, and each day post-admission
- any random combination
- CK-MB measurement for ruling out MI is:
- highly sensitive, but not very specific
- highly specific, but no very sensitive
- is both highly sensitive and specific
- is neither highly sensitive nor specific
Use the following Key to answer Questions 5-12:
- 1,2, and 3 are correct
- 1 and 3 are correct
- 2 and 4 are correct
- only 4 is correct
- all are correct
- Which of the following are types of arrhythmias?
- tachycardia
- cardiomyopathy
- bradycardia
- myocarditis
- Measurement of serum myoglobin is not very useful for ruling out MI because:
- it is present in too low concentrations
- levels rise and fall too rapidly (<12 hrs.) and is not useful for individuals who appear late.
- there are no specific assays to measure myoglobin
- it is not specific for cardiac disease
- Which of the following drugs are used for the treatment of arrythmias?
- beta-blockers
- digoxin
- diuretics
- quinidine
- Pathological disorders of muscle can be categorized as resulting form:
- degeneration of activating neurons
- degeneration of muscle cells
- damage by trauma
- genetic abnormalities
- Which of the following is (are) true about congestive heart failure (CHF)?
- CHF is caused by a failure of the heart to pump blood.
- CHF can be diagnosed by physicians on clinical grounds and by the use of measurements of brain natriuretic peptide.
- There is an increasing prevalence of CHF.
- CHF is usually caused by cardiac rhythm abnormalities.
- Acute coronary syndromes include:
- Congestive heart failure
- Unstable angina
- Cardiomyopathy
- Myocardial infarction
- Which of the following statements is (are) true?
- CK-MB and Troponin I have the same clinical sensitivity for detecting myocardial infarction.
- ALT and LD are currently valuable markers for detecting myocardial infarction.
- Troponin I is more specific for myocardial infarction. Than are CK-MB or myoglobin.
- Troponin I should be used in preference to Troponin T.
- CK-MB is increasingly be replaced by [fill in one of the following], a more specific marker for myocardial infarction.
- Troponin I or T
- Bone natriuretic peptide
- C-reactive protein
- Tropomyosin
- Titin
- Answer
-
- a (p. 576)
- b (p. 577)
- b (p. 576)
- a (p. 576-577)
- b (p. 574)
- c (p. 578)
- c (p. 575)
- e (p. 574-575)
- a (p. 574)
- c (p. 573)
- b (p. 576-577)
- a (p. 573)