1.38: Central Nervous System
- Page ID
- 38618
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\( \newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\)
( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\id}{\mathrm{id}}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\kernel}{\mathrm{null}\,}\)
\( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\)
\( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\)
\( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\AA}{\unicode[.8,0]{x212B}}\)
\( \newcommand{\vectorA}[1]{\vec{#1}} % arrow\)
\( \newcommand{\vectorAt}[1]{\vec{\text{#1}}} % arrow\)
\( \newcommand{\vectorB}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vectorC}[1]{\textbf{#1}} \)
\( \newcommand{\vectorD}[1]{\overrightarrow{#1}} \)
\( \newcommand{\vectorDt}[1]{\overrightarrow{\text{#1}}} \)
\( \newcommand{\vectE}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash{\mathbf {#1}}}} \)
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)Use the following key to answer Questions 1-16.
- 1,2, and 3 are correct
- 1 and 3 are correct
- 2 and 4 are correct
- only 4 is correct
- all are correct
- The Central nervous system is comprised of:
- brain
- sympathetic nerves
- spinal chord
- parasympathetic nerves
- The cerebrospinal fluid:
- is about 150 mL
- is produced and reabsorbed at a rate of about 150 mL/day
- is replaced every 4 to 6 hours
- is constant in volume
- The blood brain barrier:
- is a physiological barrier separating brain and CSF fluid from substances carried in the blood
- allows brain and CSF composition to be different
- is determined at cell surfaces of the choroid plexus
- is permeable to water
- The blood brain barrier is impermeable to:
- proteins
- carbon monoxide
- aniline dyes
- alcohol
- In the case of drugs, the ability to cross the blood brain barrier:
- is greater if it is lipid soluble
- is less if it is ionized
- is dependent upon disease status
- is dependent upon amino acid transport
- In normal CSF:
- protein levels are less than 800 mg/L
- protein levels are equal to serum
- glucose levels are 60-80% of serum
- glucose levels are equal to serum
- The brain’s energy reserve:
- is similar to that of the liver
- is primarily the lipid of adipose tissue
- is in the grey matter
- is very small
- The primary energy source(s) of the brain is/are:
- fatty acids
- triglycerides
- cholesterol
- glucose
- Factors that determine whether a molecule will be excluded from the brain by the blood-brain barrier include:
- molecular weight
- molecular polarity
- molecular ionization
- capillary permeability
- In the norepinephrine neuron the precursor amino acid tyrosine is taken up and converted to:
- levodopa
- dopamine
- phenylalanine
- norepinephrine
- Serotonin neurons within the control nervous system use which amino acid precursor(s) to form the neurotransmitter?
- tyrosine
- phenylalanine
- norepinephrine
- tryptophan
- Which of the following drugs is (are) used to treat psychiatric disorders:
- tricyclic antidepressants
- lithium
- monoamine oxidase inhibitors
- phenytoin
- When monitoring drugs such as amitriptyline and imipramine
- the type of illness should be considered
- dexamethasone depression test results should be consulted
- care must be taken to keep specimens refrigerated
- the metabolites should also be monitored
- Which of the following can act as neurotransmitters?
- acetylcholine
- gamma-amino-butyric acid
- dopamine
- norepinephrine
- Lithium is most useful for the treatment of:
- unipolar depression
- classical schizophrenia
- psychosis
- bipolar depression
- The dexamethasone suppression test of cortisol is used to confirm the diagnosis of:
- unipolar depression
- bipolar depression
- psychoses
- classic schizophrenia
- none of the above
- Antipsychotic drugs vary very little in their potency and greatly in their metabolism
- True
- False
- Answer
-
- b (p. 789)
- e (p. 789)
- e (p. 790)
- b (p. 790-791)
- a (p. 790)
- b (p. 791, 801-803)
- d (p. 792)
- d (p. 792)
- e (p. 790)
- c (p. 793)
- d (p. 793)
- a (p. 800)
- d (p. 803-804)
- e (p. 792-793)
- d (p. 800, 807)
- a (p. 801)
- b (p. 798-799)