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6.9.5: 5. Evaluation of Oropharyngeal Cancer- Key points

  • Page ID
    53882
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    Evaluation of Oropharyngeal Cancer: Key points

    • Squamous cell carcinoma (SCC) occurs most commonly
    • Etiology includes smoking and HPV infection
    • Histological diagnosis is essential, also to exclude malignancies like minor salivary cancers, melanoma, lymphoma, and inflammatory causes (e.g. TB)
    • Surgery +/- (chemo)radiation, or primary chemoradiation offers the best chance of cure
    • Objectives of preoperative evaluation
      • Confirm diagnosis
      • Staging
      • Patient evaluation: Fitness, objectives (cure vs palliation), ability to undergo surgery +/- (chemo)radiation, or primary (chemo)radiation, and ability to deal with the long-term consequences of treatment
      • Decide whether to offer curative or palliative treatment
      • Surgery
        • Plan appropriate surgery
        • Avoid inappropriate surgery
        • Avoid surgery beyond the scope of the surgeon
      • Primary chemoradiation
        • Ability to complete treatment
        • Ability to deal with long-term consequences of treatment