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6.9.11: 11. Optimal Therapeutic Approach Not Easily Defined

  • Page ID
    53888
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    Oropharyngeal cancer: Optimal therapeutic approach not easily defined

    • No valid comparative studies
      • Surgery +/- postoperative (chemo)radiation
      • Primary chemoradiation
    • No single therapeutic regimen offers clear-cut, superior survival advantage
    • Optimal approach aims for
      • Single modality treatment for early tumors
      • Minimum treatment morbidity and mortality
      • Optimal functional outcome (swallowing, speech)
      • Cost-efficiency
    • Therapeutic choice therefore requires
      • Careful review of each case
        • Staging
        • General physical condition
        • Emotional reserves
        • Social and financial support
        • Likelihood of regular follow-up
      • Availability of supportive care (including nutrition), speech and swallowing rehabilitation and salvage treatment
      • Experience of treating team