10.3: Predisposing Factors
- Page ID
- 15628
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General Factors
- Females
- Elderly
- Diabetes mellitus: The glucose in urine is a good culture medium for organisms. Diabetes also impairs the function of white blood cells and diabetic autonomic neuropathy may cause a lower motor neuron neuropathic bladder with poor bladder emptying.
- Immunocompromised patients:
- malnutrition
- HIV/AIDS
- cancer
- chemotherapy
- immunosuppression
- Analgesic abuse
- can cause papillary necrosis
Local Factors
Any condition that impairs the normal flow of urine, or interferes with normal emptying can predispose to infection.
- Obstruction of upper tracts (kidneys and ureters)
- stones
- PUJ obstruction
- sloughed papillae (diabetics)
- Bladder outflow obstruction
- urethral stricture
- post mid-urethral tape surgery
- Neuropathic bladder
- Vesico-ureteric reflux
- Foreign bodes in urinary tract
- bladder catheter
- double J ureteric stent
- Urological “procedures”
- cystoscopy
- urodynamics
- Vesico colic fistula
- Pregnancy
- Vaginal infections