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7.3.4: Prefilled Syringes

  • Page ID
    89721
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    Prefilled sterile syringes or cartridges are manufactured with a single drug dose. The prefilled syringe may come with or without a needle and with or without a plunger. If a cartridge is supplied, a reusable cartridge holder will be required.

    Follow these steps to prepare a prefilled cartridge.

    Supplies needed:

    • Provider’s order
    • Drug reference material
    • Sterile prefilled cartridge
    • Reusable cartridge holder
    • Patient’s health record
    • 1 mL syringe with ¼ to 5/8-inch 25–27 gauge safety needle
    • Bandage
    • Medication tray
    • Sharps container
    • Gloves
    1. Review the provider’s order and review drug reference material.
    2. Wash hands and don gloves.
    3. Select the right medication and check it against the provider’s order.
    4. Check the expiration date.
    5. Calculate the dose to be given.
    6. Assemble the supplies needed.
    7. Check the medication against the provider’s order.
    8. Break the seal by placing one hand on the needle cover and the other on the barrel of the prefilled cartridge. Next, move your hands together until you hear a click. If needed, remove the cover on the cartridge and attach a covered safety needle.
    9. Hold the reusable cartridge holder so the opening (for the barrel) is facing up. Pull the plunger rod out until it clicks. Turn the blue lock until it clicks to increase the space between the blue lock and the flange.
    10. Insert the cartridge into the reusable cartridge holder. To secure the cartridge, turn the blue lock on the reusable cartridge holder until it clicks to decrease the space between the blue lock and the flange. Turn the white plunger rod until it screws onto the rubber stopper.
    11. Remove needle cap. Hold the syringe unit vertically with the uncapped needle pointed upward. Tap the barrel carefully with the fingertips or a pen to move the air bubbles up to the top.
    12. Push the plunger slowly to the correct calibration marking for the ordered dose.
    13. Recap the needle using the one-hand scoop technique.
    14. Check the medication against the provider’s order.
    15. After “administering” the injection, unscrew the plunger rod and pull it out until it clicks. Turn the blue lock until it clicks to increase the space between the blue lock and the flange.
    16. Carefully invert the reusable cartridge holder over a biohazard sharps container to discard the cartridge. Hold the reusable cartridge holder firmly to avoid falling into the sharps container.
    17. Disinfect the reusable cartridge holder.
    18. Clean up the work area.

    This page titled 7.3.4: Prefilled Syringes is shared under a CC BY 4.0 license and was authored, remixed, and/or curated by Anna Jannak (Consortium of Academic and Research Libraries in Illinois (CARLI)) .

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