Supplemental Materials - Instructor Notes for Extra Credit Exercises
- Page ID
- 98947
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\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)Medication Adherence Case Study #1
AW is 50-year-old with heart failure (HFrEF Stage C NYHA Class II) is taking metoprolol, furosemide and
lisinopril. AW continues to work as a court reporter and cannot leave the proceedings once court is in
session. Create a medication plan for frequency and timing of medications around AW’s work schedule
yet optimizing the pharmacotherapy. Please consider that during the incident hospitalization for heart
failure, AW had an episode of hypotension. Also, AW has carpal tunnel syndrome and has a long
commute to work (no available restroom). AW has been skipping the furosemide and taking metoprolol
and lisinopril together on route to work; sometimes arriving to the courthouse feeling lightheaded as
AW goes through the metal detector.
Assigned Student Task #1.1:
1. Suggestion a schedule for AW to take their medications that will allow AW to take all
medications daily, safely arrive at work, and minimize hypotensive episodes. Write a brief
description of the pharmacokinetics of the various drugs that you considered when creating the
medication schedule.
Notes for Instructor:
Enter text here.
Assigned Student Task #1.2:
2. Design a pillbox! AW requested a pillbox that would be small enough to fit in a pocket. You can
be creative with the features you would like to include that may help adherence.
Notes for Instructor:
Enter text here.
Medication Adherence Case Study #2
CZ is 30-year-old with heart failure post COVID infection (HFrEF Stage C NYHA Class II) is taking
metoprolol, furosemide, and sacubitril/valsartan (Entresto). CZ has returned to work and bikes about 3
blocks to the office. Previously on the weekends CZ rode about 10 miles on a bike trail and wants to
gradually try resuming longer bike rides. Create a medication plan for frequency and timing of
medications around to optimize the pharmacotherapy and limit skipped or missed doses. CZ has been
missing the furosemide and then taking metoprolol and Entresto together at work.
Assigned Student Task #1.1:
1. Suggestion a schedule for CZ to take their medications that will allow AW to take all medications
daily, safely bike to work, minimize hypotensive episodes, and resume biking. Write a brief
description of the pharmacokinetics of the various drugs CZ is taking, which will help you to
create the medication schedule.
Notes for Instructor:
Enter text here.
Assigned Student Task #1.2:
2. Design a pillbox! CZ requested a pillbox that would be small enough to fit into biking clothes.
You can be creative with the features you would like to include that may help adherence. Also, a
bioengineering student is available for consultation.
Notes for Instructor:
Enter text here.