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4.2: Digestion and Absorption of Carbohydrates

  • Page ID
    6780
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    Learning Objectives

    • Learn about digestion and absorption of carbohydrates

    From the Mouth to the Stomach

    The mechanical and chemical digestion of carbohydrates begins in the mouth. Chewing, also known as mastication, crumbles the carbohydrate foods into smaller and smaller pieces. The salivary glands in the oral cavity secrete saliva that coats the food particles. Saliva contains the enzyme, salivary amylase. This enzyme breaks the bonds between the monomeric sugar units of disaccharides, oligosaccharides, and starches. The salivary amylase breaks down amylose and amylopectin into smaller chains of glucose, called dextrins and maltose. The increased concentration of maltose in the mouth that results from the mechanical and chemical breakdown of starches in whole grains is what enhances their sweetness. Only about five percent of starches are broken down in the mouth. (This is a good thing as more glucose in the mouth would lead to more tooth decay.) When carbohydrates reach the stomach no further chemical breakdown occurs because the amylase enzyme does not function in the acidic conditions of the stomach. But mechanical breakdown is ongoing—the strong peristaltic contractions of the stomach mix the carbohydrates into the more uniform mixture of chyme.

    fig 4.2..1.jpg
    Figure \(\PageIndex{1}\): Salivary Glands in the Mouth. Salivary glands secrete salivary amylase, which begins the chemical breakdown of carbohydrates by breaking the bonds between monomeric sugar units.

    From the Stomach to the Small Intestine

    The chyme is gradually expelled into the upper part of the small intestine. Upon entry of the chyme into the small intestine, the pancreas releases pancreatic juice through a duct. This pancreatic juice contains the enzyme, pancreatic amylase, which starts again the breakdown of dextrins into shorter and shorter carbohydrate chains. Additionally, enzymes are secreted by the intestinal cells that line the villi. These enzymes, known collectively as disaccharidase, are sucrase, maltase, and lactase. Sucrase breaks sucrose into glucose and fructose molecules. Maltase breaks the bond between the two glucose units of maltose, and lactase breaks the bond between galactose and glucose. Once carbohydrates are chemically broken down into single sugar units they are then transported into the inside of intestinal cells.

    When people do not have enough of the enzyme lactase, lactose is not sufficiently broken down resulting in a condition called lactose intolerance. The undigested lactose moves to the large intestine where bacteria are able to digest it. The bacterial digestion of lactose produces gases leading to symptoms of diarrhea, bloating, and abdominal cramps. Lactose intolerance usually occurs in adults and is associated with race. The National Digestive Diseases Information Clearing House states that African Americans, Hispanic Americans, American Indians, and Asian Americans have much higher incidences of lactose intolerance while those of northern European descent have the least.[1] Most people with lactose intolerance can tolerate some amount of dairy products in their diet. The severity of the symptoms depends on how much lactose is consumed and the degree of lactase deficiency.

    Absorption: Going to the Blood Stream

    The cells in the small intestine have membranes that contain many transport proteins in order to get the monosaccharides and other nutrients into the blood where they can be distributed to the rest of the body. The first organ to receive glucose, fructose, and galactose is the liver. The liver takes them up and converts galactose to glucose, breaks fructose into even smaller carbon-containing units, and either stores glucose as glycogen or exports it back to the blood. How much glucose the liver exports to the blood is under hormonal control and you will soon discover that even the glucose itself regulates its concentrations in the blood.

    fig 4.2.2.jpg
    Figure \(\PageIndex{2}\): Carbohydrate Digestion. Carbohydrate digestion begins in the mouth and is most extensive in the small intestine. The resultant monosaccharides are absorbed into the bloodstream and transported to the liver.

    Maintaining Blood Glucose Levels: The Pancreas and Liver

    Glucose levels in the blood are tightly controlled, as having either too much or too little glucose in the blood can have health consequences. Glucose regulates its levels in the blood via a process called negative feedback. An everyday example of negative feedback is in your oven because it contains a thermostat. When you set the temperature to cook a delicious homemade noodle casserole at 375°F the thermostat senses the temperature and sends an electrical signal to turn the elements on and heat up the oven. When the temperature reaches 375°F the thermostat senses the temperature and sends a signal to turn the element off. Similarly, your body senses blood glucose levels and maintains the glucose “temperature” in the target range. The glucose thermostat is located within the cells of the pancreas. After eating a meal containing carbohydrates glucose levels rise in the blood.

    Insulin-secreting cells in the pancreas sense the increase in blood glucose and release the hormone, insulin, into the blood. Insulin sends a signal to the body’s cells to remove glucose from the blood by transporting it into different organ cells around the body and using it to make energy. In the case of muscle tissue and the liver, insulin sends the biological message to store glucose away as glycogen. The presence of insulin in the blood signifies to the body that glucose is available for fuel. As glucose is transported into the cells around the body, the blood glucose levels decrease. Insulin has an opposing hormone called glucagon. Glucagon-secreting cells in the pancreas sense the drop in glucose and, in response, release glucagon into the blood. Glucagon communicates to the cells in the body to stop using all the glucose. More specifically, it signals the liver to break down glycogen and release the stored glucose into the blood, so that glucose levels stay within the target range and all cells get the needed fuel to function properly.

    fig 4.2.3.jpg
    Figure \(\PageIndex{3}\): The Regulation of Glucose.

    Leftover Carbohydrates: The Large Intestine

    Almost all of the carbohydrates, except for dietary fiber and resistant starches, are efficiently digested and absorbed into the body. Some of the remaining indigestible carbohydrates are broken down by enzymes released by bacteria in the large intestine. The products of bacterial digestion of these slow-releasing carbohydrates are short-chain fatty acids and some gases. The short-chain fatty acids are either used by the bacteria to make energy and grow, are eliminated in the feces, or are absorbed into cells of the colon, with a small amount being transported to the liver. Colonic cells use the short-chain fatty acids to support some of their functions. The liver can also metabolize the short-chain fatty acids into cellular energy. The yield of energy from dietary fiber is about 2 kilocalories per gram for humans, but is highly dependent upon the fiber type, with soluble fibers and resistant starches yielding more energy than insoluble fibers. Since dietary fiber is digested much less in the gastrointestinal tract than other carbohydrate types (simple sugars, many starches) the rise in blood glucose after eating them is less, and slower. These physiological attributes of high-fiber foods (i.e. whole grains) are linked to a decrease in weight gain and reduced risk of chronic diseases, such as Type 2 diabetes and cardiovascular disease.

    fig 4.2.4.jpg
    Figure \(\PageIndex{4}\): Overview of Carbohydrate Digestion.

    A Carbohydrate Feast

    You are at a your grandma’s house for family dinner and you just consumed kalua pig, white rice, sweet potatoes, mac salad, chicken long rice and a hot sweet bread roll dripping with butter. Less than an hour later you top it off with a slice of haupia pie and then lie down on the couch to watch TV. The “hormone of plenty,” insulin, answers the nutrient call. Insulin sends out the physiological message that glucose is abundant in the blood, so that cells can absorb it and either use it or store it. The result of this hormone message is maximization of glycogen stores and all the excess glucose, protein, and lipids are stored as fat.

    fig 4.2.5.jpg
    Figure \(\PageIndex{5}\): Carbohydrate feast.

    A typical American Thanksgiving meal contains many foods that are dense in carbohydrates, with the majority of those being simple sugars and starches. These types of carbohydrate foods are rapidly digested and absorbed. Blood glucose levels rise quickly causing a spike in insulin levels. Contrastingly, foods containing high amounts of fiber are like time-release capsules of sugar. A measurement of the effects of a carbohydrate-containing food on blood-glucose levels is called the glycemic response.

    Glycemic Index

    The glycemic responses of various foods have been measured and then ranked in comparison to a reference food, usually a slice of white bread or just straight glucose, to create a numeric value called the glycemic index (GI). Foods that have a low GI do not raise blood-glucose levels neither as much nor as fast as foods that have a higher GI. A diet of low-GI foods has been shown in epidemiological and clinical trial studies to increase weight loss and reduce the risk of obesity, Type 2 diabetes, and cardiovascular disease.[2]

    Table \(\PageIndex{1}\): The Glycemic Index: Foods In Comparison To Glucose.

    Foods GI Value
    Low GI Foods (< 55)
    Apple, raw 36
    Orange, raw 43
    Banana, raw 51
    Mango, raw 51
    Carrots, boiled 39
    Taro, boiled 53
    Corn tortilla 46
    Spaghetti (whole wheat) 37
    Baked beans 48
    Soy milk 34
    Skim milk 37
    Whole milk 39
    Yogurt, fruit 41
    Yogurt, plain 14
    Icecream 51
    Medium GI Foods (56–69)
    Pineapple, raw 59
    Cantaloupe 65
    Mashed potatoes 70
    Whole-wheat bread 69
    Brown rice 55
    Cheese pizza 60
    Sweet potato, boiled 63
    Macaroni and cheese 64
    Popcorn 65
    High GI Foods (70 and higher)
    Banana (over-ripe) 82
    Corn chips 72
    Pretzels 83
    White bread 70
    White rice 72
    Bagel 72
    Rice milk 86
    Cheerios 74
    Raisin Bran 73
    Fruit roll-up 99
    Gatorade 78

    For the Glycemic Index on different foods, visit http://www.mendosa.com/gilists.htm.

    The type of carbohydrate within a food affects the GI along with its fat and fiber content. Increased fat and fiber in foods increases the time required for digestion and delays the rate of gastric emptying into the small intestine which, ultimately reduces the GI. Processing and cooking also affects a food’s GI by increasing their digestibility. Advancements in the technologies of food processing and the high consumer demand for convenient, precooked foods in the United States has created foods that are digested and absorbed more rapidly, independent of the fiber content. Modern breakfast cereals, breads, pastas, and many prepared foods have a high GI. In contrast, most raw foods have a lower GI. (However, the more ripened a fruit or vegetable is, the higher its GI.)

    The GI can be used as a guide for choosing healthier carbohydrate choices but has some limitations. The first is GI does not take into account the amount of carbohydrates in a portion of food, only the type of carbohydrate. Another is that combining low- and high-GI foods changes the GI for the meal. Also, some nutrient-dense foods have higher GIs than less nutritious food. (For instance, oatmeal has a higher GI than chocolate because the fat content of chocolate is higher.) Lastly, meats and fats do not have a GI since they do not contain carbohydrates.

    more resources

    Visit this online database to discover the glycemic indices of foods. Foods are listed by category and also by low, medium, or high glycemic index.
    http://www.gilisting.com/

    Footnotes

    1. Lactose Intolerance. National Digestive Diseases Information Clearing House. digestive.niddk.nih.gov/ddise...seintolerance/. Updated April 23, 2012. Accessed September 22, 2017. ↵
    2. Brand-Miller J, et al. Dietary Glycemic Index: Health Implications. J Am Coll Nutr. 2009; 28(4), 446S–49S.https://www.ncbi.nlm.nih.gov/pubmed/20234031. Accessed September 27, 2017. ↵

    Contributors and Attributions


    This page titled 4.2: Digestion and Absorption of Carbohydrates is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by The University of Hawaiʻi via source content that was edited to the style and standards of the LibreTexts platform; a detailed edit history is available upon request.