The primary site of carbohydrate digestion is in the lumen of the small intestine, where pancreatic amylase begins the digestion of starch granules (amylose and amylopectin). Disaccharides such as mal...The primary site of carbohydrate digestion is in the lumen of the small intestine, where pancreatic amylase begins the digestion of starch granules (amylose and amylopectin). Disaccharides such as maltase and isomaltase on the intestinal brush border then complete the degradation and are hydrolyzed to their constituent monosaccharides by enzymes on the brush border, and the monosaccharides released are absorbed into the enterocyte.