The page discusses the advancements and impact of selective immunosuppression in solid organ and bone marrow transplantation. Immunosuppression helps reduce organ graft rejection and graft-vs-host dis...The page discusses the advancements and impact of selective immunosuppression in solid organ and bone marrow transplantation. Immunosuppression helps reduce organ graft rejection and graft-vs-host disease (GVHD) by targeting specific immune pathways while minimizing side effects.
The page outlines the principles of clinical cancer chemotherapy, highlighting different chemotherapy efficacy levels, from curative to limited effectiveness, and the mechanisms of drug resistance in ...The page outlines the principles of clinical cancer chemotherapy, highlighting different chemotherapy efficacy levels, from curative to limited effectiveness, and the mechanisms of drug resistance in cancer treatment. It discusses the impact of first-order kinetics in chemotherapy, types of drugs used (based on cell cycle specificity), their mechanisms, and associated toxicities.