32: Weight Management Drugs

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32.0: Introduction
This page addresses the prevalence and implications of overweight and obesity in the U.S., noting that nearly 75% of adults and 20% of children are affected, and that global obesity rates have tripled in the last 50 years. It highlights health risks such as diabetes and cardiovascular disease, alongside an economic burden of approximately $173 billion in medical costs.
32.1: Introduction to Weight Management
This page covers the complex interplay of genetics, lifestyle, and environmental factors contributing to obesity and overweight, emphasizing their health risks like heart disease and diabetes. It addresses hormonal impacts, particularly in postmenopausal women, and highlights the importance of psychological factors and geographical disparities in obesity prevalence.
32.2: Anorexiants
This page discusses anorexiant drugs for weight management, including their benefits, risks, and nursing implications. It highlights substances like phentermine and benzphetamine, emphasizing their appetite-suppressing and metabolism-stimulating effects alongside potential misuse and serious side effects. Key contraindications include advanced arteriosclerosis and severe hypertension.
32.3: Lipase Inhibitors
This page discusses the role of lipase inhibitors, particularly orlistat, in weight management by decreasing dietary fat absorption. It details indications, actions, adverse reactions, and contraindications, emphasizing gastrointestinal side effects and caution needed in specific groups. It also addresses nursing implications like monitoring weight and lab values and advises on dietary changes and vitamin supplementation for clients.
32.4: Other Drugs, Supplements, and Herbal Remedies
This page covers drugs and herbal supplements for weight management, focusing on GLP-1 receptor agonists like semaglutide and liraglutide, as well as P-1 receptor antagonists such as bupropion naltrexone. Both categories emphasize the importance of monitoring for weight, blood pressure, and mental health. Additionally, various dietary supplements like CLA, glucomannan, and green tea extract are discussed for their effects and nursing implications.
32.5: Chapter Summary
This page distinguishes between overweight and obesity, exploring their mechanisms and clinical signs. It discusses pharmacological options for weight management, including anorexiants, lipase inhibitors, and herbal remedies. Emphasizing the importance of lifestyle changes like exercise and caloric restriction, it notes that these may not always be sufficient, necessitating further medications or supplements.
32.6: Key Terms
This page provides an overview of key nutrition and metabolic health concepts, including BMI, metabolic syndrome, and clean eating. It discusses physiological processes like circadian rhythms and insulin resistance, and conditions associated with obesity, such as cholelithiasis and sleep apnea. Dietary considerations, notably the Mediterranean diet and nutrient-dense foods, are highlighted, along with societal issues like weight bias and stigma.
32.7: Review Questions
This page discusses weight management, focusing on Body Mass Index (BMI) for assessing overweight and obesity. It includes patient assessment scenarios and medication prescriptions, emphasizing crucial education on weight-loss medications like benzphetamine, phentermine, orlistat, and bupropion-naltrexone. The effects, side effects, and the need for monitoring client progress are highlighted, aiming to improve healthcare providers' understanding of effective weight management strategies.

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