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- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/00%3A_Front_Matter
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.11%3A_Lipid_Lowering_Drugs_-_Hyperlipidemia_and_AtherosclerosisThe page provides a comprehensive overview of atherosclerosis, a chronic inflammatory disease affecting arterial walls in long-lived mammals, caused by risk factors such as hypertension, diabetes, and...The page provides a comprehensive overview of atherosclerosis, a chronic inflammatory disease affecting arterial walls in long-lived mammals, caused by risk factors such as hypertension, diabetes, and dyslipoproteinemia. It discusses the role of various lipoproteins, transmembrane receptors, apolipoproteins, and sterols in lipid transport and metabolism.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)The object of this text is to teach students an approach to the study of pharmacologic agents. The focus is on the basic principles of biophysics, biochemistry and physiology, as related to the mechan...The object of this text is to teach students an approach to the study of pharmacologic agents. The focus is on the basic principles of biophysics, biochemistry and physiology, as related to the mechanisms of drug action, biodistribution and metabolism. The course consists of lectures and student-led case discussions.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.16%3A_Antimicrobials_I_and_IIThis page covers the pharmacologic principles of antimicrobial therapy, explaining that successful therapy involves delivering an effective drug concentration to the infection site for an appropriate ...This page covers the pharmacologic principles of antimicrobial therapy, explaining that successful therapy involves delivering an effective drug concentration to the infection site for an appropriate duration. It highlights key elements like drug absorption, distribution, and elimination, emphasizing that bacteriocidal therapy is crucial for certain infections.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.07%3A_Local_AnestheticsThe page discusses the mechanisms of local anesthesia, focusing on the pharmacology of local anesthetics (LAs). It explains how LAs selectively numb a specific body region by blocking nerve impulses, ...The page discusses the mechanisms of local anesthesia, focusing on the pharmacology of local anesthetics (LAs). It explains how LAs selectively numb a specific body region by blocking nerve impulses, primarily by interfering with sodium channel activity. Different forms of LAs have varying potencies and effectiveness based on their molecular structure and pH environment.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/00%3A_Front_Matter/02%3A_InfoPageThe LibreTexts libraries are Powered by MindTouch ® and are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the Californ...The LibreTexts libraries are Powered by MindTouch ® and are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the California State University Affordable Learning Solutions Program, and Merlot.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/zz%3A_Back_Matter/10%3A_Index
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.15%3A_Neuropharmacology_III_-_AnticonvulsantsThis page discusses seizures, specifically focusing on anticonvulsant drugs and treatments. Seizures are episodes of abnormal neuron activity, often leading to altered consciousness and motor activity...This page discusses seizures, specifically focusing on anticonvulsant drugs and treatments. Seizures are episodes of abnormal neuron activity, often leading to altered consciousness and motor activity, with epilepsy affecting about 1% of the population. Effective treatment relies on correct diagnosis and classification, with partial and primary generalized seizures as key categories.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.12%3A_Neuropharmacology_I_-_Drugs_for_Movement_DisordersThis page provides a comprehensive overview of movement disorders, particularly focusing on Parkinson's Disease (PD) and its treatment options. Movement disorders are neurologic disorders affecting th...This page provides a comprehensive overview of movement disorders, particularly focusing on Parkinson's Disease (PD) and its treatment options. Movement disorders are neurologic disorders affecting the motor system, with Parkinson's being the most prevalent, especially in those over 65. The page discusses the symptoms and pathology of PD, highlighting dopamine's role.
- https://med.libretexts.org/Bookshelves/Pharmacology_and_Neuroscience/Book%3A_Principles_of_Pharmacology_(Rosow_Standaert_and_Strichartz)/01%3A_Chapters/1.18%3A_Opioid_PharmacologyThe page provides a comprehensive overview of opioids and their classification, structure-activity relationships, endogenous opioid peptides, pharmacodynamics, and pharmacokinetics. It distinguishes b...The page provides a comprehensive overview of opioids and their classification, structure-activity relationships, endogenous opioid peptides, pharmacodynamics, and pharmacokinetics. It distinguishes between opiates, opioids, and various opioid receptor subtypes (??, ??, ??), and describes the effects and mechanisms of action of opioid agonists and antagonists. The document also covers clinical properties, such as analgesia, sedation, respiratory depression, and effects on smooth muscle.
