Skip to main content
Medicine LibreTexts

3.2: Screening For Red and Yellow Flags

  • Page ID
    59125
  • \( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)

    \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)

    \( \newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\)

    ( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\)

    \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)

    \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\)

    \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)

    \( \newcommand{\Span}{\mathrm{span}}\)

    \( \newcommand{\id}{\mathrm{id}}\)

    \( \newcommand{\Span}{\mathrm{span}}\)

    \( \newcommand{\kernel}{\mathrm{null}\,}\)

    \( \newcommand{\range}{\mathrm{range}\,}\)

    \( \newcommand{\RealPart}{\mathrm{Re}}\)

    \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)

    \( \newcommand{\Argument}{\mathrm{Arg}}\)

    \( \newcommand{\norm}[1]{\| #1 \|}\)

    \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)

    \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\AA}{\unicode[.8,0]{x212B}}\)

    \( \newcommand{\vectorA}[1]{\vec{#1}}      % arrow\)

    \( \newcommand{\vectorAt}[1]{\vec{\text{#1}}}      % arrow\)

    \( \newcommand{\vectorB}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)

    \( \newcommand{\vectorC}[1]{\textbf{#1}} \)

    \( \newcommand{\vectorD}[1]{\overrightarrow{#1}} \)

    \( \newcommand{\vectorDt}[1]{\overrightarrow{\text{#1}}} \)

    \( \newcommand{\vectE}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash{\mathbf {#1}}}} \)

    \( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)

    \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)

    \(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)

    Red flags are signs and symptoms that raise suspicion of serious underlying pathology, if a serious pathology is suspected a clinical decision should be made to refer the patient to an appropriate healthcare practitioner.

    • Red Flags for Back Pain – For patients with low back pain there are several serious spinal pathologies to be aware of, these are cauda equina syndrome, spinal fracture, malignancy, and spinal infection (Finucane et al., 2020).

    Yellow flags are psychosocial and occupational factors that may affect patient presentation and treatment approaches and outcomes.

    PhysioTutors: Screening for Red Flags

    PhysioTutors: What are Yellow Flags and Why are They Important?

    References and Sources

    Artus, M., Campbell, P., Mallen, C. D., Dunn, K. M., & van der Windt, D. A. (2017). Generic prognostic factors for musculoskeletal pain in primary care: a systematic review. BMJ open, 7(1), e012901. doi:10.1136/bmjopen-2016-012901

    Cook, C. E., George, S. Z., & Reiman, M. P. (2018). Red flag screening for low back pain: nothing to see here, move along: a narrative review. British journal of sports medicine, 52(8), 493–496. doi:10.1136/bjsports-2017-098352

    Finucane, L. M., Downie, A., Mercer, C., Greenhalgh, S. M., Boissonnault, W. G., Pool-Goudzwaard, A. L., Beneciuk, J. M., Leech, R. L., & Selfe, J. (2020). International Framework for Red Flags for Potential Serious Spinal Pathologies. The Journal of orthopaedic and sports physical therapy, 50(7), 350–372. https://doi.org/10.2519/jospt.2020.9971

    Galliker, G., Scherer, D. E., Trippolini, M. A., Rasmussen-Barr, E., LoMartire, R., & Wertli, M. M. (2020). Low Back Pain in the Emergency Department: Prevalence of Serious Spinal Pathologies and Diagnostic Accuracy of Red Flags. The American journal of medicine, 133(1), 60–72.e14. https://doi.org/10.1016/j.amjmed.2019.06.005

    Green, D. J., Lewis, M., Mansell, G., Artus, M., Dziedzic, K. S., Hay, E. M., … van der Windt, D. A. (2018). Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials. European journal of pain (London, England), 22(6), 1057–1070. doi:10.1002/ejp.1190

    Hayden, J. A., Wilson, M. N., Riley, R. D., Iles, R., Pincus, T., & Ogilvie, R. (2019). Individual recovery expectations and prognosis of outcomes in non-specific low back pain: prognostic factor review. The Cochrane database of systematic reviews, 2019(11), CD011284. doi:10.1002/14651858.CD011284.pub2

    Heck, A. & Sigel, K. (2019). The Assessment Book – Physiotutors Guide to Orthopedic Physical Assessment (3rd ed.). Physiotutors.

    Kim, Y. J. (2019). Red flag rules for knee and lower leg differential diagnosis. Annals of translational medicine, 7(Suppl 7), S250. doi:10.21037/atm.2019.07.62

    Parreira, P., Maher, C. G., Traeger, A. C., Hancock, M. J., Downie, A., Koes, B. W., & Ferreira, M. L. (2019). Evaluation of guideline-endorsed red flags to screen for fracture in patients presenting with low back pain. British journal of sports medicine, 53(10), 648–654. doi:10.1136/bjsports-2018-099525

    Premkumar, A., Godfrey, W., Gottschalk, M. B., & Boden, S. D. (2018). Red Flags for Low Back Pain Are Not Always Really Red: A Prospective Evaluation of the Clinical Utility of Commonly Used Screening Questions for Low Back Pain. The Journal of bone and joint surgery. American volume, 100(5), 368–374. doi:10.2106/JBJS.17.00134

    Protheroe, J., Saunders, B., Bartlam, B., Dunn, K. M., Cooper, V., Campbell, P., … Foster, N. E. (2019). Matching treatment options for risk sub-groups in musculoskeletal pain: a consensus groups study. BMC musculoskeletal disorders, 20(1), 271. doi:10.1186/s12891-019-2587-z

    Shaw, B., Kinsella, R., Henschke, N., Walby, A., & Cowan, S. (2020). Back pain “red flags”: which are most predictive of serious pathology in the Emergency Department?. European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 29(8), 1870–1878. https://doi.org/10.1007/s00586-020-06452-1

    Thomas, L., & Treleaven, J. (2020). Should we abandon positional testing for vertebrobasilar insufficiency?. Musculoskeletal science & practice, 46, 102095. https://doi.org/10.1016/j.msksp.2019.102095

    Tseli, E., Boersma, K., Stålnacke, B. M., Enthoven, P., Gerdle, B., Äng, B. O., & Grooten, W. (2019). Prognostic Factors for Physical Functioning After Multidisciplinary Rehabilitation in Patients With Chronic Musculoskeletal Pain: A Systematic Review and Meta-Analysis. The Clinical journal of pain, 35(2), 148–173. doi:10.1097/AJP.0000000000000669

    Tsiang, J. T., Kinzy, T. G., Thompson, N., Tanenbaum, J. E., Thakore, N. L., Khalaf, T., & Katzan, I. L. (2019). Sensitivity and specificity of patient-entered red flags for lower back pain. The spine journal: official journal of the North American Spine Society, 19(2), 293–300. doi:10.1016/j.spinee.2018.06.342


    This page titled 3.2: Screening For Red and Yellow Flags is shared under a CC BY 4.0 license and was authored, remixed, and/or curated by Richard Lebert (eCampus Ontario) via source content that was edited to the style and standards of the LibreTexts platform.