Normal Blood Cells
- Page ID
- 70220
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\( \newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\)
( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\id}{\mathrm{id}}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\kernel}{\mathrm{null}\,}\)
\( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\)
\( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\)
\( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\AA}{\unicode[.8,0]{x212B}}\)
\( \newcommand{\vectorA}[1]{\vec{#1}} % arrow\)
\( \newcommand{\vectorAt}[1]{\vec{\text{#1}}} % arrow\)
\( \newcommand{\vectorB}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vectorC}[1]{\textbf{#1}} \)
\( \newcommand{\vectorD}[1]{\overrightarrow{#1}} \)
\( \newcommand{\vectorDt}[1]{\overrightarrow{\text{#1}}} \)
\( \newcommand{\vectE}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash{\mathbf {#1}}}} \)
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
Polymorphonuclear Segmented Neutrophil (PMN)
- Cell size: 10-16 microns
- N/C ratio 1:1
- 2-5 distinct nuclear lobes (filament connecting lobes)
- Central or eccentric nucleus
- Deep blue-purple coarsely granular nuclear chromatin (distinct parachromatin)
- No nucleoli
- Abundant pink cytoplasm
- Fine violet-pink specific granules
PMN \(\PageIndex{}\)
Band Neutrophil
- Cell size: 10-16 microns
- N/C ratio 1:1
- Elongated narrow band shape of uniform thickness, singular lobe
- Central or eccentric nucleus
- Deep blue-purple coarsely granular nuclear chromatin (distinct parachromatin)
- No nucleoli
- Abundant pink cytoplasm
- Fine violet-pink specific granules
Band \(\PageIndex{}\)
Eosinophil
- Cell size: 10-16 microns
- N/C ratio 1:1
- 2 distinct nuclear lobes - rarely 3 or 4 (filament connecting)
- Central or eccentric nucleus
- Deep blue-purple coarsely granular nuclear chromatin
- No nucleoli
- Abundant pink cytoplasm
- Large red, uniform specific granules
Eosinophil \(\PageIndex{}\)
Basophil
- Cell size: 10-16 microns
- N/C ratio 1:1
- 2 distinct nuclear lobes - rarely 3 or 4 (filament connecting)
- Central or eccentric nucleus
- Deep blue-purple coarsely granular nuclear chromatin
- No nucleoli
- Abundant pale blue cytoplasm
- Coarse purple-black non-uniform specific granules (water soluble - may dissolve in staining)
Basophil \(\PageIndex{}\)
Monocyte
- Cell size: 12-20 microns
- N/C ratio 2:1 or 1:1
- Cerebriform or horseshoe shaped nucleus
- Central nucleus
- Blue-purple, fine reticular nuclear chromatin (less distinct parachromatin)
- 0-2 Nucleoli
- Abundant pale gray-blue cytoplasm. May see pseudopodia and vacuoles
- Numerous very fine (dust like) red granules evenly dispersed
Monocyte \(\PageIndex{}\)
Lymphocyte
- Cell size: 7-18 microns (usually 9-12)
- N/C ratio 4:1 (occasionally 3:1)
- Round or indented nucleus
- Eccentric nucleus often with scanty cytoplasm
- Homogeneous, coarse blue-purple nuclear chromatin (smudged)
- Nucleoli often absent but may see in mature forms
- Light to dark blue cytoplasm, scanty to moderate
- Occasionally a few azurophilic granules seen
Small Lymph \(\PageIndex{}\)
Average to Large Lymph \(\PageIndex{}\)
Reactive Lymphocyte
- Activated T-Lymph
- Wandering or Ballerina skirt cytoplasm often indented by adjacent red blood cells
- Bluer cytoplasm periphery especially where indented by red blood cells
- Nucleus also has wandering appearance
- Coarser nuclear chromatin
Reactive Lymph \(\PageIndex{}\)
Plasmacytoid Lymphocyte
- Activated B- Lymph
- Generally considered a lymph transitioning to a plasma cell
- Slightly larger with darker royal blue cytoplasm and more heavily clumped chromatin
- May lack very eccentric nucleus and well developed golgi of plasma cell
Plasmacytoid Lymph \(\PageIndex{}\)
Red Blood Cell
- Cell size: 6-8 microns
- Clear pink to red cytoplasm, central pallor 1/3 of cell diameter
- No cytoplasmic granules
RBC\(\PageIndex{}\)
Platelet
- Cell size: 2-4 microns
- Light blue, fragment of megakaryocyte cytoplasm
- Evenly dispersed, fine red-purple granules
Platelet \(\PageIndex{}\)