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5.5: Celiac Disease

  • Page ID
    1095
  • [ "article:topic", "Celiac Disease", "gluten", "authorname:blindshield" ]

    1 out of every 133 people in the United States has celiac disease1. People with celiac disease cannot consume the protein gluten because it causes their body to generate an autoimmune response (immune cells attack the body's own cells) that causes damage to the villi in the intestine (Figure \(\PageIndex{1}\)).

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    Figure \(\PageIndex{1}\): Different stages of celiac disease. Image used with permission (CC BY-SA 4.0; WikipedianProlific)

    This damage to the villi impairs the absorption of macronutrients and micronutrients from food. There are a variety of symptoms for celiac disease that vary depending on age and from person to person. For a listing of all symptoms, see the first link below. The second link describes the difficulty in diagnosing this disease, which is reinforced by the third video link.

    What is gluten?

    Gluten is a protein that is bound to starch in the endosperm of grains such as: Wheat, Barley, Rye and Triticale (Figure \(\PageIndex{2}\)).

    clipboard_e0ab5bf30afd57c838f7ba7b3de53de9f.png

    Figure \(\PageIndex{2}\): Parts of a wheat granule. Image used with permission (CC BYSA 3.0;  Jon C ).

    Gluten-free diets have been increasing in popularity even for people who don’t have celiac disease. The thinking among those consuming these diets is that they might be gluten-sensitive, meaning that they experience adverse effects from consuming it. However, as the following videos describes, there is not much evidence to support people being gluten-sensitive.

    Videos and Link

    Contributors