Three B vitamins are involved in what is known as 1-carbon metabolism. This is the movement of 1 carbon units, generally methyl groups ($$\ce{CH3}$$). It is similar to the movement of the amino group that occurs in transamination. As shown in the figure below, folate, vitamin $$B_{12}$$, and vitamin $$B_6$$ are the B vitamins involved in 1-carbon metabolism.
Vitamin $$B_6$$ has been described in the previous chapter, so this chapter is going to focus on folate and vitamin $$B_{12}$$. We will examine this figure in pieces, so that hopefully by the time this chapter is completed, you will understand the role of all these vitamins in 1-carbon metabolism.
Query $$\PageIndex{1}$$