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12: The Endocrine System

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    128645
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    • 12.1: An Overview of the Endocrine System
      Communication is a process in which a sender transmits signals to one or more receivers to control and coordinate actions. In the human body, two major organ systems participate in relatively “long distance” communication: the nervous system and the endocrine system. Together, these two systems are primarily responsible for maintaining homeostasis in the body.
    • 12.2: Hormones
      Although a given hormone may travel throughout the body in the bloodstream, it will affect the activity only of its target cells; that is, cells with receptors for that particular hormone. Once the hormone binds to the receptor, a chain of events is initiated that leads to the target cell’s response. Hormones play a critical role in the regulation of physiological processes because of the target cell responses they regulate.
    • 12.3: The Pituitary Gland and Hypothalamus
      The hypothalamus–pituitary complex can be thought of as the “command center” of the endocrine system. This complex secretes several hormones that directly produce responses in target tissues, as well as hormones that regulate the synthesis and secretion of hormones of other glands. In addition, the hypothalamus–pituitary complex coordinates the messages of the endocrine and nervous systems.
    • 12.4: Thyroid Gland and Parathyroid Glands
      A butterfly-shaped organ, the thyroid gland is located anterior to the trachea, just inferior to the larynx. The medial region, called the isthmus, is flanked by wing-shaped left and right lobes. Each of the thyroid lobes are embedded with parathyroid glands, primarily on their posterior surfaces. The tissue of the thyroid gland is composed mostly of thyroid follicles. The follicles are made up of a central cavity filled with a sticky fluid called colloid.
    • 12.5: Adrenal Glands
      The adrenal glands, located on the superior surface of the kidneys, release the hormones aldosterone, which regulates blood sodium concentrations, glucocorticoid hormones such as cortisol that regulate blood glucose levels and long-term stress responses, and epinephrine and norepinephrine that stimulate the fight-or-flight stress response.
    • 12.6: Endocrine Pancreas
      The pancreas is a long, slender organ, most of which is located posterior to the bottom half of the stomach. Although it is primarily an exocrine gland, secreting a variety of digestive enzymes, the pancreas has an endocrine function. Its pancreatic islets—clusters of cells formerly known as the islets of Langerhans—secrete the hormones glucagon, insulin, somatostatin, and pancreatic polypeptide.
    • 12.7: Review Questions


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