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Medicine LibreTexts

Essentials of Physiology for Nurse Anesthetists I (Gopalan)

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This textbook provides a comprehensive overview of key physiological systems relevant to nurse anesthetists, emphasizing their role in patient care and anesthesia management. It covers foundational topics such as cell physiology, neurophysiology, and the autonomic nervous system, which are critical for understanding nerve signaling, synaptic transmission, and muscle function—essential concepts in anesthesia. The text also explores endocrine regulation, cardiovascular physiology, renal function, and blood composition, highlighting their impact on hemodynamics and drug metabolism. Through a detailed examination of sensory physiology and pain mechanisms, the book equips nurse anesthetists with the knowledge necessary to optimize pain management and anesthesia delivery. By integrating these physiological principles, the textbook serves as a valuable resource for developing a deep understanding of anesthesia’s effects on the body and improving patient outcomes.

Thumbnail: Capt. Petra Spencer, student registered nurse anesthetist, William Beaumont Army Medical Center, helps “Jeff” go to sleep for surgery during a training exercise using simulation technology for emergent-based scenarios that nurse anesthetists commonly run into during surgery, Aug. 2, 2019, at the El Paso Veterans Affairs Healthcare System surgical room. (Public Domain; Defense Visual Information Distribution Service)


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