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4.1: Anatomical Terminology

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    69858
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    Resource

    The nervous system is one of the most complex systems that we know of. Parts of this system malfunction frequently, and the results are a wide range of neurological disorders that affect humans, from injury to genetic disorders. The gross anatomy of the nervous system is an important foundation to the studies of other aspects of neuroscience. This chapter covers some of the major anatomical structures in the nervous system.

    Divisions of the Nervous System

    Broadly speaking, the nervous system can be divided into two main categories: The central nervous system (CNS) and the peripheral nervous system (PNS). Simply put, the CNS is the brain and spinal cord, while the PNS is all the other nerve cells in the body in the periphery. The two systems are not isolated from each other; information passes rapidly between the PNS and the CNS, and vice versa. When a signal that originates in the PNS moves to the CNS, we sometimes say that the signal is incoming or ascending, while the CNS to PNS direction is outgoing or descending. Information that arrives into the CNS is also called an afferent signal, while information leaving the CNS is an efferent signal. These two terms are frequently confused, but you can use the knowledge of other words that start with “e” to remember that an “exit” or an “escape” is something that moves away for ‘efferent’, and “arrive” for ‘afferent’. Alternatively, an efferent signal is something that has an effect on the outside world, while an afferent signal affects the person.

    Illustration of two bodies showing the central and peripheral nervous systems. Details in caption.
    Figure 21.1. The nervous system is divided into the central nervous system, which includes the brain and spinal cord, and the peripheral nervous system, which includes the cranial and spinal nerves. Information traveling toward the brain is called afferent, whereas information traveling from the brain is called efferent. ‘CNS and PNS’ by Casey Henley is licensed under a Creative Commons Attribution Non-Commercial Share-Alike (CC BY-NC-SA) 4.0 International License.

    Anatomically, the CNS consists of two organs, the brain and the spinal cord. The brain is the main organ where movement originates, where thoughts and plans develop, and where consciousness is housed. The brain is what pushes us to act on our drives and desires, where language begins, and where memories are stored. The intact adult brain weighs about 1.5 kg (3 pounds), which is barely 2% of total body weight. Despite this relatively small size, it is extremely power hungry, and uses up about one-fifth of the body’s total energy expenditure.

    Anatomical Terms

    When talking about parts of the brain, it is helpful to have a set of directional terms that can describe the location of various anatomical structures unambiguously.

    Familiarity with the terminology used to describe location and relationships within the nervous system is critical as we move forward into examining brain systems.

    Directional Terms

    Directional terms are used to locate one structure, usually in relation to another structure. Some terms, like dorsal or ventral, are relative to the axis of the central nervous system, so the direction these terms define changes if used for brain regions versus other body regions. Other terms, like superior or inferior, keep their meaning across the entire body.

    • Anterior: In front of; toward the face
    • Posterior: Behind; toward the back
    • Superior: Above; toward the head
    • Inferior: Below; toward the feet
    • Medial: Toward the middle
    • Lateral: Toward the edge
    • Dorsal: Toward the top of the brain or the back of the spinal cord
    • Ventral: Toward the bottom of the brain or the front of the spinal cord
    • Rostral: Toward the front of the brain or the top of the spinal cord
    • Caudal: Toward the back of the brain or the bottom of the spinal cord

    Often anterior and rostral are used interchangeably and posterior and caudal are used interchangeably.

    Neuroanatomists use all of these terms to describe the relationship of one structure to another. For example, we’ll see in Chapter 22 that introduces the four lobes of the brain, the frontal lobe is anterior or rostral to the parietal lobe, and the parietal lobe is dorsal to the temporal lobe. These anatomical words can also be combined to subdivide complex brain regions. For example, a structure called the thalamus has many small subsections, such as the dorsomedial nucleus or the ventropostero-lateral nucleus. Naming structures with this anatomical language is useful in identifying where they are located in a brain scan or autopsy, but these words tell us nothing about function.

    Illustration of a body and a brain showing directional anatomical terms. Details in caption and text.
    Figure 21.2. Directional terms used to locate nervous system structures. The dorsal / ventral and rostral / caudal pairs point in different directions depending on if they are referring to the axis of the brain (orange arrows) or the axis of the spinal cord (blue arrows). The definitions of each term are described in the text. ‘Anatomical Directions’ by Casey Henley is licensed under a Creative Commons Attribution Non-Commercial Share-Alike (CC BY-NC-SA) 4.0 International License.

    Visualizing the Brain: Anatomical Planes

    As a three-dimensional structure, the brain can be sectioned, or cut, for visualization or analysis in several ways. Here, we will describe the three main orientations, each at right angles to the others.

    1. The frontal or coronal plane is a vertical plane in a medial to lateral direction, dividing objects into front and back pieces.
    2. The sagittal plane is also a vertical plane but in a rostral-caudal direction, meaning it divides objects into right and left regions.
    3. Finally, the horizontal plane divides objects into top and bottom regions.
    Illustrations of anatomical planes and brain slices created by those planes. Details in caption.
    Figure 21.3. Three anatomical planes are used to divide the nervous system to be able to view internal regions and structures. The frontal or coronal plane is a vertical plane that runs parallel to the eyes or ears and will divide the body into front and back regions. The sagittal plane is a vertical plane that runs perpendicular to the eyes or ears and will divide the body into left and right regions. The horizontal plane runs parallel to the ground and will divide the body into top and bottom regions. ‘Anatomical Planes’ by Casey Henley is licensed under a Creative Commons Attribution Non-Commercial Share-Alike (CC BY-NC-SA) 4.0 International License.

    Gray Matter and White Matter

    In a sliced section of the brain, you might notice that brain tissue has different colored areas. Some brain tissue is pale and almost white, and these areas are described as white matter. Generally, white matter represents pathways of communication. White matter regions are comprised of axons. It appears white due to the myelin sheath on the axons. Other sections of brain tissue have a darker pink/gray color, appropriately called gray matter. These areas are usually dense with cell bodies and dendrites. Gray matter is the location of most synapses.

    Illustration of a frontal brain section showing white and gray matter. Details in caption.
    Figure 21.4. The central nervous system tissue can be divided into white and gray matter. White matter is primarily myelinated axons. Gray matter is primarily neuronal cell bodies and dendrites. In the brain, the surface of the cerebral cortex is a layer of gray matter. White matter can be found below the gray matter layer and is the location of the axons traveling to and from the cortical cell layer. Gray matter can also be found deep in the brain in subcortical regions that play critical roles in behavior. ‘White and Gray Matter’ by Casey Henley is licensed under a Creative Commons Attribution Non-Commercial Share-Alike (CC BY-NC-SA) 4.0 International License.

    White Matter Tracts

    The brain has two very similar halves, the left and right hemisphere. Oftentimes, in the neurotypical individual, information passes between both hemispheres rapidly: what one hemisphere senses or learns, so does the other hemisphere. It is the white matter tracts that allow for this transfer of information. When a white matter pathway crosses from one side of the body to another, we call it a decussation.

    Commissures are white matter tracts that connect gray matter between the left and right hemispheres of the brain. The main commissure that allows for the passage of information between the two hemispheres is called the corpus callosum.

    Association fibers are white matter tracts that connect different bits of gray matter within the same hemisphere of the brain. These connections do not cross the midline.

    Projection fibers are white matter tracts that connect the hemispheres of the brain with lower brain structures or with the spinal cord. They “project” from the cortex to the lower brain structures or spinal cord.

    Image of white matter connections within the brain. Details in the caption and text.
    Figure 21.5. Commissures (red) connect gray matter between the left and right hemispheres. Association fibers (blue) connect gray matter within the same hemisphere of the brain. Projection fibers (green) connect gray matter with lower brain structures or the spinal cord. ‘White Matter Connections’ by Valerie Hedges is licensed under a Creative Commons Attribution Non-Commercial Share-Alike (CC-BY-NC-SA) 4.0 International License.

    Key Takeaways

    • Anatomical terminology is critical for determining neurological landmarks and discussing the anatomy of the nervous system

    Test Yourself!

    An interactive H5P element has been excluded from this version of the text. You can view it online here:
    https://openbooks.lib.msu.edu/introneuroscience1/?p=128#h5p-30

    Attributions

    Portions of this chapter were remixed and revised from the following sources:

    1. Foundations of Neuroscience by Casey Henley. The original work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License
    2. Open Neuroscience Initiative by Austin Lim. The original work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

    Media Attributions


    4.1: Anatomical Terminology is shared under a CC BY-NC-SA 4.0 license and was authored, remixed, and/or curated by LibreTexts.

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