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11: One-Carbon Metabolism Micronutrients

Three B vitamins are involved in what is known as 1-carbon metabolism. This is the movement of 1 carbon units, generally methyl groups (CH3). It is similar to the movement of the amino group that occurs in transamination. Folate, vitamin B12, and vitamin B6 are the B vitamins involved in 1-carbon metabolism.

Thumbnail: The chemical structure of pyridoxal phosphate, a form of vitamin B6. Image used with permission (Public Domain; Fvasconcellos).