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12.4: Diagnosis

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Usually confirmed on cystoscopy (under general or regional anaesthesia): Petechial bleeding is seen from the bladder wall (particularly after second filling of the bladder with irrigation fluid). There is usually a small bladder capacity and rarely an area of ulceration of the bladder wall (Hunner’s ulcer).

Differential Diagnosis

IC is a diagnosis of exclusion.

  1. Cystitis – urine dipstick and culture
  2. TB – urine for AFBs and TB culture
  3. Bladder carcinoma (particularly CIS) – urine cytology
  4. Bladder stone – U/S and cystoscopy
  5. Pelvic infection
  6. Endometriosis Intravesical Potassium Test If instillation of a solution with high potassium concentration reproduces the patient’s pain this is diagnositic of IC.

This page titled 12.4: Diagnosis is shared under a CC BY-NC-SA 2.5 license and was authored, remixed, and/or curated by Stephen Jeffery and Peter de Jong via source content that was edited to the style and standards of the LibreTexts platform.

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